Long noncoding RNA AC096655.1-002 has been officially named as gastric cancer-associated transcript 1, GACAT1

Jun 2013

Bingxiu Xiao, Junming Guo

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Long noncoding RNA AC096655.1-002 has been officially named as gastric cancer-associated transcript 1, GACAT1

Bingxiu Xiao Junming Guo 0 ) Zhejiang Provincial Key Laboratory of Pathophysiology, Ningbo University School of Medicine , Ningbo 315211, China - Shortly after the article entitled Decreased expression of long noncoding RNA AC096655.1-002 in gastric cancer and its clinical significance published in Tumor Biology [1], the long noncoding RNA AC096655.1-002 that studied in this paper has been officially named by HUGO Gene Nomenclature Committee (HGNC). Readers can find the detail information from Human Gene Nomenclature Database (www.genenames.org/hgnc-searches). Its HGNC ID is HGNC: 48336. Its synonym is AC096655.1-002, LINC00876, long intergenic non-protein coding RNA 876. Its gene is located at 2q12.3. As long noncoding RNA AC096655.1-002 was first found associated with gastric cancer, the committee has named it as gastric cancer-associated transcript 1, GACAT1. That is, approved symbol is GACAT1 and approved name is gastric cancer-associated transcript 1 (http://www.genenames.org/data/ hgnc_data.php?hgnc_id=48336). GACAT1 has been found significantly downregulated in gastric cancer tissues compared with paired-adjacent non-tumorous tissues. Its expression level was significantly correlated with lymph node metastasis, distant metastasis, TNM stages, and differentiation [1]. These results indicated that GACAT1 may be a potential biomarker in the diagnosis of gastric carcinoma. Conflicts of interest None (...truncated)


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Bingxiu Xiao, Junming Guo. Long noncoding RNA AC096655.1-002 has been officially named as gastric cancer-associated transcript 1, GACAT1, 2013, pp. 3271-3271, Volume 34, Issue 5, DOI: 10.1007/s13277-013-0916-7