Clinician performance and prominence of diagnoses displayed by a clinical diagnostic decision support system.
Clinician Performance and Prominence of Diagnoses Displayed by a
Clinical Diagnostic Decision Support System
Eta S. Berner, EdD, Richard S. Maisiak, PhD, MSPH,
Gustavo R. Heudebert, MD and K. Randall Young, Jr., MD
University of Alabama at Birmingham, Birmingham, AL
ABSTRACT
Clinical decision support systems (CDSS) can impact
both diagnostic and therapeutic decision-making, but
physicians sometimes fail to heed the appropriate
CDSS advice, or become influenced in a negative
way by the CDSS.
This study examined the
relationships among clinicians' prior diagnostic
accuracy, theperformance of a diagnostic CDSS, and
how the CDSS influenced the accuracy of the
clinician's subsequent diagnoses. Results showed
that (1) clinicians who already were considering the
correct diagnosisprior to using the CDSS were more
likely to get the CDSS to produce the correct
diagnosis in a prominent position than those not
considering it initially; (2) physicians are strongly
anchored by their initial diagnoses prior to using the
CDSS; and (3) changes in the clinicians' diagnoses
after using the CDSS are related to presence or
absence of the correct diagnosis in the top 10
diagnoses displayed by the CDSS.
INTRODUCTION
Clinical decision support systems (CDSS) have been
shown to decrease medication errors and improve
diagnostic decision-making. 1-3 Groups such as
Leapfrog and others have advocated the use of
reminder and alerting systems and interest in
computerized provider order entry with clinical
decision support is increasing. 4 Although these
systems are clearly capable of influencing physicians
in a positive manner, there are also reports in the
published literature that physicians may fail to alter
their original wrong decisions, or worse, may change
correct decisions to incorrect ones after using
CDSS. 2'5'6 For instance, Teich et al. found that some
decisions were easier to influence than others. In
particular, they commented that it is difficult to get
physicians to change plans they had already made. 5
Galanter et al. published an article describing a
situation where a CDSS provided an alert of a
medication overdose that the attending clinician
repeatedly ignored. 6 On the other hand, Friedman et
al, in an article documenting the effectiveness
of two diagnostic decision support systems mentions
that sometimes their subjects switched from the
correct diagnosis to an incorrect one after using the
system. 3
Although Friedman et al.'s subjects
improved more when the CDSS provided the correct
diagnosis, it was not immediately clear what factors
related to what Friedman et al. termed "negative
consultations." It is possible that the CDSS provided
misleading information that caused the subjects to
change, or that the subjects did not attend to or
understand what they were viewing in spite of
accurate CDSS information.
Similarly, in other
studies where the CDSS provided useful information
that was not acted upon, it is not clear whether the
subjects were anchored to a prior course of action or
whether there was some other reason for failing to
heed the suggestions. As CDSS move out of the
research arena and into practice settings, it becomes
important not just to document when they are
effective, but also to systematically examine the
situations in which they do not work a~ intended.
Such data are important for improving the CDSS as
well as for instructing users on the most appropriate
ways to utilize the CDSS output.
This paper provides an analysis of the impact of
CDSS performance on diagnostic decision-making.
Studies of the impact of diagnostic CDSS have
tended to examine how the physician performs
without examining in detail the what the CDSS
actually provided, other than the correct diagnosis
being present on the CDSS list.2'3 Only by examining
the CDSS performance can we begin to understand
how it influences clinician performance. In the
present study we examined the effect on physician
diagnostic performance of the presentation of the
correct diagnosis in a prominent or less prominent
position in the output of a diagnostic CDDS.
Although we focused on a diagnostic system, the
issue of the factors that lead a CDSS to change, or
fail to change, clinician decision-making is important
for all kinds of CDSS.
AMIA 2003 Symposium Proceedings − Page 76
METHODS
The subjects were 70 internal medicine residents who
took part in a study examining the effects of training
and practice on use of a diagnostic decision support
system. The diagnostic decision support system was
Quick Medical Reference (QMWM), version 3.8.5
marketed by First DataBank. It was available via the
Internet on a server running Citrix Metaframe,
version 1.8 and Windows NT, version 4.0. These
residents had all been given two to four hours of
training on the use of QMR, had QMR available
online for use for a two-month period and then used
QMR to assist them with the diagnosis of four
diagnostically challenging paper and pencil cases.
The cases were selected from a previous sample of
diagnostically challenging cases. 7 Although all of the
cases were rare and/or atypical, the correct diagnosis
(based on definitive test results) was in QMR's
knowledge base and, with optimal use of QMR,
appeared within the top 20 of QMR's suggestions.
Subjects reviewed the case, prepared their own
differential diagnosis, used QMR in any manner they
chose, and then revised their differential diagnosis.
A maximum of 20 diagnoses were allowed. For each
case, subjects saved the last QMR screen they were
looking at as a text file. This permitted determination
of whether the correct diagnosis was either being
actively considered by the resident and/or or
presented to them as a possibility by QMR. Thus,
there were a total of 280 cases analyzed. For eight
cases, the screens were inadvertently not saved and
those cases are excluded from further analyses,
making the total analyzed 272.
Final diagnosis-For each case, this was scored
correct if the correct diagnosis was included on the
resident's final differential after using the CDSS and
incorrect if the correct diagnosis was not included on
the differential.
For each case we determined the resident's unaided
diagnosis, the position of the correct diagnosis on the
last QMR screen saved for that case, and the
resident's final diagnosis.
Table 1
Unaided diagnosis--For each case, this was scored
correct if the correct diagnosis was included on the
resident's initial differential prior to using the CDSS
and incorrect if the correct diagnosis was not
included.
Position of the correct diagnosis on the last screen
s a v e d - R a n k of the correct diagnosis as displayed o n
QMR's screen. The top diagnosis was rank 1. We
grouped the ranks into strata of five as shown in
Tables 2 and 3. We considered display within the top
two strata (e.g, first ten diagnoses on the list) as a
prominent position. Previous research testing QMR
performance in a more artificial situation has shown
that when QMR displays the c (...truncated)