Addressing global health equity through Global Collaborative Evidence Networks: a narrative literature review of governance models, power and participation
Pilla et al. Globalization and Health
(2026) 22:28
https://doi.org/10.1186/s12992-026-01192-1
Globalization and Health
Open Access
RESEARCH
Addressing global health equity through
Global Collaborative Evidence Networks:
a narrative literature review of governance
models, power and participation
Bianca Pilla1*, Kylie Porritt1 and Zoe Jordan1
Abstract
Background Global Health Equity is increasingly threatened by interconnected global crises that expose systemic
inequities in health systems, global health governance and evidence infrastructures. Global Collaborative Evidence
Networks have emerged as mechanisms for mobilising knowledge, fostering interdisciplinary collaboration, and
supporting decision-making across diverse contexts to address Global Health Equity. However, their potential is
constrained by persistent challenges related to governance, inclusion, and power asymmetries. This review critically
examines the conceptual, structural, and governance dimensions of Global Collaborative Evidence Networks to assess
their potential and limitations in advancing Global Health Equity.
Methods A narrative literature review was conducted in July 2024, searching PubMed, Scopus, Web of Science,
Embase, CINAHL, and grey literature sources. A thematic analysis of 162 included studies was conducted using Braun
and Clarke’s reflexive approach to identify themes and sub-themes.
Results The review found that while Global Health Equity has emerged as a key normative framework shaped by
historical, political, and socio-economic structures, its operationalisation remains fragmented, particularly in global
governance and research systems. Global Collaborative Evidence Networks, positioned as vehicles to advance
Global Health Equity, demonstrate considerable potential yet often reproduce entrenched power asymmetries.
Substantial gaps remain in how equity, diversity, and inclusion are conceptualised and operationalised within these
networks. Although many promote shared purpose and trust-based collaboration, participation and influence often
concentrated in high-income institutions, reinforcing systemic and resource asymmetries. Key tensions, such as
between efficiency and inclusiveness, unity and diversity, and centralisation and decentralisation, shape governance
dynamics and impact who benefits from network participation. Despite the proliferation of equity-focused
frameworks in global health partnerships, none have been adapted for networks, and accountability mechanisms
remain weak. Theoretical perspectives from network typologies and governance modes offer valuable perspectives
but require integration with intersectional and decolonial approaches to address persistent power imbalances.
*Correspondence:
Bianca Pilla
Full list of author information is available at the end of the article
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Pilla et al. Globalization and Health
(2026) 22:28
Page 2 of 16
Conclusion Global Collaborative Evidence Networks are a powerful mechanism for supporting and strengthening
evidence-based decision-making to address global health inequities. However, they risk replicating existing inequities
without deliberate, equity-centred governance. This review calls for the development of empirically grounded,
context-sensitive frameworks to guide the equitable, diverse and inclusive design, evaluation, and governance of
Global Collaborative Evidence Networks.
Keywords Global health equity, Global Collaborative Evidence Networks, Network typologies, Network theory,
Governance, Equity, Diversity and inclusion
Background
Global health equity (GHE) faces unprecedented challenges in an era marked by multifaceted and interrelated
global crises. Various intersecting global challenges—
including climate crises, environmental disasters, escalating cybercrime, political conflict and polarisation, mass
migration, global inflation, debt crises, and pandemics—are straining efforts to advance global health equity
and achieve healthcare objectives at local, national, and
international levels. This unprecedented “polycrisis” significantly threatens the attainment of the United Nations
Sustainable Development Goals (UN SDGs) and the
overall well-being of people worldwide [1, 2].
This pressure crucible has exposed structural and
systemic weaknesses in the global evidence ecosystem
on various fronts, including global inequities in public
health capacities [3]. GHE is a fundamental, yet evolving
concept rooted in social justice, human rights, and the
fair distribution of health resources across diverse populations [4, 5]. It is an approach based on values and rights
that reflects a desire to reduce disadvantage, discrimination, and marginalisation [6]. Achieving GHE requires a
robust evidence ecosystem that facilitates the co-production, translation, and dissemination of knowledge across
institutional, national, and disciplinary boundaries [7, 8].
Global Collaborative Evidence Networks (GCENs) have
emerged as key mechanisms in this effort, fostering interdisciplinary research dissemination, knowledge sharing
and translation [9], particularly in low-resource settings
[10, 11]. However, despite their potential, GCENs face
significant challenges related to equitable governance,
inclusivity, power asymmetries, and sustainability [12,
13]. Moreover, there is a dearth of research on how they
can function more effectively and efficiently, specifically, how equity, diversity, and inclusion are understood
and measured. Clear guidance on how GCENs should
be structured, managed or governed to advance GHE is
lacking. Yet, how GCENs are governed will have significant implications for their ability to help reduce global
health disparities and ‘leave no one behind’ [7, 14].
As an emerging network typology, limited research
has focused on conceptualising GCENs within network research. Before guidance on governing equitable,
diverse and inclusive GCENs to advance GHE is developed, we first need to explore the t (...truncated)