Regulation of SPRY3 by X chromosome and PAR2-linked promoters in an autism susceptibility region

Human Molecular Genetics, 2015, Vol. 24, No. 25 7450 doi: 10.1093/hmg/ddv448 Advance Access Publication Date: 2 November 2015 Erratum E R R AT U M Regulation of SPRY3 by X chromosome and PAR2-linked promoters in an autism susceptibility region Human Molecular Genetics 2015 24:18; pp. 5126–5141; doi: 10.1093/hmg/ddv231 The original submitted version of this manuscript used a nomenclature for SPRY3 core promoter ‘AG repeat’ alleles that was revised during the review process. Unfortunately, a residual labelling error was retained in the final published manuscript. To correct this error, on the X-axis of the graph in Fig. 5D, please change ‘309’ to ‘306’; ‘309 Egr1’ to ‘306 Egr1’; ‘327’ to ‘324’; ‘327 Egr1’ to ‘324 Egr1’. All other graph labels and the figure legend are correct. The correct figure is reproduced here: The Publisher apologises for this error. Figure 5. Regulation of SPRY3 promoter alleles by TFs. Effect of transient over-expression of TFs on human SPRY3/357-LacZ promoter reporter expression in human JAR cells: (A) EGR1; (C) ZNF263; (E) MAZ; (F) PURA; (G) PAX6. (B) Dose-response of EGR1 expression vector DNA on reporter expression. (D) Expression of SPRY3/306-LacZ, SPRY3/ 324-LacZ, and SPRY3/357-LacZ promoter allele reporter vectors to 2 μg EGR1 expression vector. Vertical axis denotes reporter expression level. Means ± SEM of three replicates. *P < 0.05; **P < 0.01; ***P < 0.001. © The Author 2015. Published by Oxford University Press. All rights reserved. For Permissions, please email: 7450 Zhenfei Ning, Andrew S. McLellan, Melanie Ball, Freda Wynne, Cora O’Neill, Walter Mills, John P. Quinn, Dirk A. Kleinjan, Richard J. Anney, Ruaidhre J. Carmody, Gerard O’Keeffe and Tom Moore  (...truncated)