National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) Polypeptide Hormones, Subunits, and Antisera Available to Qualified Investigators, for Research

217 NATIONAL INSTITUTE OF DIABETES AND DIGESTIVE AND KIDNEY DISEASES (NIDDK) POLYPEPTIDE HORMONES, SUBUNITS, AND ANTISERA AVAILABLE TO QUALIFIED INVESTIGATORS, FOR RESEARCH APPLICATION: Application forms must be submitted prior to an award. Letters of request not accompanied by an application form are not acceptable. Forms are available from and should be submitted to: Dr. Salvatore Raiti, Director, National Hormone and Pituitary Program, 210 West Fayette Street, Suite 505, Baltimore, MD 21201.Voice PHONE: (410) 706-2746; FAX PHONE: (410) 837-9566; BITNET: "" AWARDS: Only one ampoule or one RIA kit of each material will be awarded at a time. Requests for larger amounts of materials may be granted, subject to review by the Hormone Distribution Program Advisory Committee. NEW MATERIALS AVAILABLE 1. NEW, MONOSPECIFIC POLYCLONAL ANTISERA to Rat PRL, GH, FSHP, LH3, and TSHPI 2. NEW, SENSITIVE ANTISERUM for RAT LH RIA 3. Rat GH and PRL FREE OF HORMONAL CONTAMINANTS 4. Ovine, Bovine, Porcine FSH DEVOID OF LH FOR RIA: Pituitary & Placental Hormones & Subunits, Antisera & Reference Preparations Human AS RP H a 1 - -1 b 1 - 1 1 1 - 1 - CG Intact 1 CGa Subunit 1 CGP Subunit 1 a b b FSH Intact i FSHa Subunit 1 FSH3 Subunit 1 a Variant 1 1 1 - LH Intact le 1 LHa LH, LPHI Subunit Subunit 1 1 1C 1 1d 1 1 1 GH GH, 20K PRL TSH TSHa TSH (PTH) b 1h cg a i PL 1b Intact Subunit Subunit Rat H ACTH k - Ovine Bovine Porcine Monkey AS RP H AS RP H AS H AS RP - - - - - - - - - - 1 1 11C 1P * 1 * * * H - AS RP - - 1 1 1 1 b 1 1 * b 1 1 1 1 1h 1 1 1 1 1 b b - a 1b 1 1 1 - j . b 1 - _ * * 1 1 1' 1 - 1 1 1c 1 - 1 1 C 1 1 1 1 1 1 1 1 1 * 1 1 1 1 -- - - 1 - 1 - - 1 - 1 1c 1 1 1 - 1 b 1 - - - - e 5. Rat LH, FSH, and TSH Subunits/Antisera 6. Glycosylated Ovine & Porcine PRL 7. 20K Variant of hGH 8. Bovine FSH RIA 9. Antiserum to cAMP _ 1 1 1 1b 1 - - b - 1g g 1 g 1 1 - - - b 1 * * 1b * * * * 1 2g * - * - - H, Hormone for lodination; AS, Diluted Antiserum for 10,000 RIAs or as indicated; RP, Reference Preparation. 5S0,ug; b1 0 0 ,ag; C200 jig; d3 0 0 jpg; e400 jig; 500 g; 91 mg; h2 mg; '5 mg; Antisera for 2,500 RIAs; Antisera for 3,750 RIAs; 'Antisera for 5,000 RIAs; mAntisera for 9,750 RIAs. "These materials will be shipped frozen by air express in the U.S.A.; ORequest antiserum to ovine FSH, for bovine FSH RIA; PRequest antiserum to ovine FSH, for porcine FSH RIA. *These materials may be obtained from Dr. A. F. Parlow, Harbor-UCLA Medical Center, 1000 West Carson Street, Torrance, CA 90509. NOTE: RIAs for ovine pituitary hormones cross-react strongly with, and may be used for the measurement of, the corresponding bovine pituitary hormones, with the exception of FSH. RIAs for rat pituitary hormones cross-react strongly with, and may be used for the measurement of the corresponding mouse pituitary hormones, with the exception of PRL. For mouse PRL, use the available homologous RIA. For mouse GH, RIA, use the available mouse GH for iodination with rat GH antiserum. RIAs for human pituitary GH, PRL, and TSH cross-react strongly with the corresponding monkey pituitary hormones. Antisera are distributed in liquid or lyophilized form. Antisera for RIA contain merthiolate if distributed in liquid form. The materials listed below are procured through programs supported by the National Institute of Diabetes and Digestive and Kidney Diseases, the Center for Population Research of the National Institute of Child Health and Human Development, and the Agricultural Research Service of the U.S. Department of Agriculture, and Dr. A.F. Parlow of the Harbor-UCLA Medical Center. These materials are distributed to qualified investigators for research purposes, not for therapeutic, diagnostic, or commercial uses. 218 For Biologic Studies: Human CG CGa CG hybrid (ABIER-CR-lxy) FSH Rat 1 mg 1 mg 1.5 mg 2 mg GH 10 mg GH, 20K Variant LH 1 mg 5 mg PRL 2 mg PRL, Glycosylated TSH -2 mg Polypeptide Hormones & Other Materials Ovine Bovine Porcine - 10 mg 10 mg 10 mg 10 mg 5 mg 10 mg - 50 mg 10 mg 5 mg - - mg 1 mg 1 mg 1 mg - - . . - - 0.50 mg 5 mg 50 mg - 5 mg - - - - LH-FSH-RH (GnRH) - - - - - - 0.2 U - 100 Ig - 80 g 100 I.g 1 mg 500 ml 1 mg 10 mg 0.1 mg 1 mg PITUITARY GLANDS, FROZEN, HUMAN U.S. Investigators only. Not for clinical investigation. ANTISERA FOR IMMUNOCYTOCHEMISTRY (undiluted or in low dilution) hGH natural, hGH synthetic, hPRL, hFSHP, hLHp, hTSHP, and hACTH rGH, rPRL, rFSHB, rLHp3, rTSHP, and mouse GH rEstrogen Receptor (ER) Antibody and Synthetic ER Peptide (amino acids 270-284) oLH3 and oPRL 1 1 1 1 OTHER ANTISERA Aldosterone antiserum Somatomedin-C antiserum (polyclonal) Somatomedin-C antiserum (monoclonal) 1 ampoule 1 ampoule 1 ampoule ampoule ampoule ampoule each ampoule HYPOTHALAMI, LYOPHILIZED, RAT MATERIALS WHICH ARE AVAILABLE THROUGH THE COURTESY OF DR. A. F. PARLOW The antisera listed below may be obtained by writing directly to Dr. A. F. Parlow, Director, Pituitary Hormones and Antisera Center, Harbor-UCLA Medical Center, 1000 West Carson Street, Torrance, CA 90509. Phone: (310) 222-3537; FAX Phone: (310) 222-3432; BITNET: "" RIA Kits Canine Chicken Equine Hamster Mouse Rabbit GH 1 1 1 - 1 1 PRL 1 1 1 1 1 1 FSH LH TSH 1 1 - - RP 1 - RP 1 RP 1 1 1 . 1,1 kit; RP, Preference Preparation FOR MATERIALS OTHER THAN THOSE LISTED ABOVE, INQUIRE OF DR. SALVATORE RAITI OR DR. A. F. PARLOW. - Insulin (guinea pig) Insulin (desotapeptide) Follistatin (recombinant) Follistatin (recombinant) - ... Folliculostatin Reference Preparation" LH-FSH-RH (GnRH) Porcine follicular fluid (bottle)" PTH (BIO) Relaxin Other -  (...truncated)