Current Biomarker Findings

An international, peer-reviewed, open access journal publishing original research, reports, reviews and commentaries on all areas of biomarker research.

List of Papers (Total 88)

Urine volatile organic compounds composition in mice bearing breast and melanoma tumors: effect of low-protein diet

Urine volatile organic compounds composition in mice bearing breast and melanoma tumors: effect of low-protein diet Jacob Gopas,1,2 Amir Abd EL Qader,3 Carol Isaacson,4 David Eichler,5 Yehuda Zeiri3,6 1The Shraga Segal Department of Microbiology, Immunology and Genetics, Ben-Gurion University of the Negev, 2The Department of Oncology, Soroka University Medical Center, Beer-Sheva...

Urine volatile organic compounds composition in mice bearing breast and melanoma tumors: effect of low-protein diet

Urine volatile organic compounds composition in mice bearing breast and melanoma tumors: effect of low-protein diet Jacob Gopas,1,2 Amir Abd EL Qader,3 Carol Isaacson,4 David Eichler,5 Yehuda Zeiri3,6 1The Shraga Segal Department of Microbiology, Immunology and Genetics, Ben-Gurion University of the Negev, 2The Department of Oncology, Soroka University Medical Center, Beer-Sheva...

Improved monitoring dynamics through use of a tethered enzyme biosensor to detect and quantify neuron-specific enolase activity levels in biofluids

Improved monitoring dynamics through use of a tethered enzyme biosensor to detect and quantify neuron-specific enolase activity levels in biofluids Roy Cohen, Jacquelyn L Nelson, Chinatsu Mukai, Alexander J Travis Baker Institute for Animal Health, College of Veterinary Medicine, Cornell University, Ithaca, NY, USA Purpose: Neuron-specific enolase (NSE) is an isoform of the...

Improved monitoring dynamics through use of a tethered enzyme biosensor to detect and quantify neuron-specific enolase activity levels in biofluids

Improved monitoring dynamics through use of a tethered enzyme biosensor to detect and quantify neuron-specific enolase activity levels in biofluids Roy Cohen, Jacquelyn L Nelson, Chinatsu Mukai, Alexander J Travis Baker Institute for Animal Health, College of Veterinary Medicine, Cornell University, Ithaca, NY, USA Purpose: Neuron-specific enolase (NSE) is an isoform of the...

Differential prognostic values of mRNA expression of CEACAM gene family members in nonsmall cell lung cancer

Differential prognostic values of mRNA expression of CEACAM gene family members in nonsmall cell lung cancer Haruhiko Nakamura,1,2 Hiroki Sakai,1 Tomoyuki Miyazawa,1 Toshiaki Somehara,2 Noboru Nakayama,2 Kiyonaga Fujii,2 Toshihide Nishimura2 1Department of Chest Surgery, 2Department of Translational Medicine Informatics, St Marianna University School of Medicine, Kawasaki...

Differential prognostic values of mRNA expression of CEACAM gene family members in nonsmall cell lung cancer

Differential prognostic values of mRNA expression of CEACAM gene family members in nonsmall cell lung cancer Haruhiko Nakamura,1,2 Hiroki Sakai,1 Tomoyuki Miyazawa,1 Toshiaki Somehara,2 Noboru Nakayama,2 Kiyonaga Fujii,2 Toshihide Nishimura2 1Department of Chest Surgery, 2Department of Translational Medicine Informatics, St Marianna University School of Medicine, Kawasaki...

MicroRNAs as potential biomarkers in malignant pleural mesothelioma

MicroRNAs as potential biomarkers in malignant pleural mesothelioma Eric Santoni-Rugiu, Morten Andersen, Morten Grauslund Laboratory of Molecular Pathology, Department of Pathology, Rigshospitalet, Copenhagen University Hospital, Copenhagen, Denmark Abstract: Malignant pleural mesothelioma (MPM), a highly lethal cancer strictly related to asbestos exposure, is usually...

MicroRNAs as potential biomarkers in malignant pleural mesothelioma

MicroRNAs as potential biomarkers in malignant pleural mesothelioma Eric Santoni-Rugiu, Morten Andersen, Morten Grauslund Laboratory of Molecular Pathology, Department of Pathology, Rigshospitalet, Copenhagen University Hospital, Copenhagen, Denmark Abstract: Malignant pleural mesothelioma (MPM), a highly lethal cancer strictly related to asbestos exposure, is usually...

Biomarkers for bipolar disorder: current insights

Biomarkers for bipolar disorder: current insights Angela Duong,1 Bushra Syed,1 Gustavo Scola2,3 1Department of Pharmacology and Toxicology, 2Department of Psychiatry, University of Toronto, 3Centre for Addiction and Mental Health, Toronto, ON, Canada Abstract: Currently, there exists a lack of definitive diagnostic tools for neuropsychiatric disorders, particularly molecular...

Biomarkers for bipolar disorder: current insights

Biomarkers for bipolar disorder: current insights Angela Duong,1 Bushra Syed,1 Gustavo Scola2,3 1Department of Pharmacology and Toxicology, 2Department of Psychiatry, University of Toronto, 3Centre for Addiction and Mental Health, Toronto, ON, Canada Abstract: Currently, there exists a lack of definitive diagnostic tools for neuropsychiatric disorders, particularly molecular...

A multi-biomarker disease activity score for monitoring rheumatoid arthritis

A multi-biomarker disease activity score for monitoring rheumatoid arthritis Shintaro Hirata,1 Nadine Defranoux,2 Kentaro Hanami,1 Kunihiro Yamaoka,3 Yoshiya Tanaka1 1The First Department of Internal Medicine, School of Medicine, University of Occupational and Environmental Health, Kitakyushu, Japan; 2Crescendo Bioscience, South San Francisco, CA, USA; 3Division of Rheumatology...

A multi-biomarker disease activity score for monitoring rheumatoid arthritis

A multi-biomarker disease activity score for monitoring rheumatoid arthritis Shintaro Hirata,1 Nadine Defranoux,2 Kentaro Hanami,1 Kunihiro Yamaoka,3 Yoshiya Tanaka1 1The First Department of Internal Medicine, School of Medicine, University of Occupational and Environmental Health, Kitakyushu, Japan; 2Crescendo Bioscience, South San Francisco, CA, USA; 3Division of Rheumatology...

Biomarker discovery in systemic sclerosis: state of the art

Biomarker discovery in systemic sclerosis: state of the art Francesco Bonella,1 Giuseppe Patuzzo,2 Claudio Lunardi2 1Interstitial and Rare Lung Disease Unit, Ruhrlandklinik University Hospital, University of Duisburg-Essen, Essen, Germany; 2Department of Medicine, University of Verona, Verona, Italy Abstract: Systemic sclerosis (SSc) is an autoimmune disease characterized by...

Biomarker discovery in systemic sclerosis: state of the art

Biomarker discovery in systemic sclerosis: state of the art Francesco Bonella,1 Giuseppe Patuzzo,2 Claudio Lunardi2 1Interstitial and Rare Lung Disease Unit, Ruhrlandklinik University Hospital, University of Duisburg-Essen, Essen, Germany; 2Department of Medicine, University of Verona, Verona, Italy Abstract: Systemic sclerosis (SSc) is an autoimmune disease characterized by...

MicroRNA signatures as clinical biomarkers in lung cancer

MicroRNA signatures as clinical biomarkers in lung cancer Athina Markou, Martha Zavridou, Evi S Lianidou Analysis of Circulating Tumor Cells, Lab of Analytical Chemistry, Department of Chemistry, University of Athens, Athens, Greece Abstract: Even if early lung cancer detection has been recently significantly improved, the invasive nature of current diagnostic procedures, and a...

MicroRNA signatures as clinical biomarkers in lung cancer

MicroRNA signatures as clinical biomarkers in lung cancer Athina Markou, Martha Zavridou, Evi S Lianidou Analysis of Circulating Tumor Cells, Lab of Analytical Chemistry, Department of Chemistry, University of Athens, Athens, Greece Abstract: Even if early lung cancer detection has been recently significantly improved, the invasive nature of current diagnostic procedures, and a...

Idiopathic pulmonary fibrosis biomarkers: clinical utility and a way of understanding disease pathogenesis

Idiopathic pulmonary fibrosis biomarkers: clinical utility and a way of understanding disease pathogenesis Matthew Flynn, Elisabeth S Baker, Daniel J Kass Dorothy P and Richard P Simmons Center for Interstitial Lung Disease, Division of Pulmonary, Allergy, and Critical Care Medicine, University of Pittsburgh, Pittsburgh, PA, USA Abstract: Idiopathic pulmonary fibrosis (IPF) is a...

Idiopathic pulmonary fibrosis biomarkers: clinical utility and a way of understanding disease pathogenesis

Idiopathic pulmonary fibrosis biomarkers: clinical utility and a way of understanding disease pathogenesis Matthew Flynn, Elisabeth S Baker, Daniel J Kass Dorothy P and Richard P Simmons Center for Interstitial Lung Disease, Division of Pulmonary, Allergy, and Critical Care Medicine, University of Pittsburgh, Pittsburgh, PA, USA Abstract: Idiopathic pulmonary fibrosis (IPF) is a...

Improving tuberculosis diagnostics with biomarkers

Improving tuberculosis diagnostics with biomarkers Chin-Chung Shu,1,2 Jann-Yuan Wang,2 Li-Na Lee,2,3 Chong-Jen Yu,2 Kwen-Tay Luh3 1Department of Traumatology, 2Department of Internal Medicine, 3Department of Laboratory Medicine, National Taiwan University Hospital, Taipei, Taiwan Abstract: Although many laboratory methods have been developed to expedite the diagnosis of active...

Improving tuberculosis diagnostics with biomarkers

Improving tuberculosis diagnostics with biomarkers Chin-Chung Shu,1,2 Jann-Yuan Wang,2 Li-Na Lee,2,3 Chong-Jen Yu,2 Kwen-Tay Luh3 1Department of Traumatology, 2Department of Internal Medicine, 3Department of Laboratory Medicine, National Taiwan University Hospital, Taipei, Taiwan Abstract: Although many laboratory methods have been developed to expedite the diagnosis of active...

Blood and cerebrospinal fluid markers in Parkinson's disease: current biomarker findings

Blood and cerebrospinal fluid markers in Parkinson's disease: current biomarker findings Claire Henchcliffe Department of Neurology, Weill Cornell Medical College, New York, NY, USA Abstract: Parkinson’s disease (PD) is a common, progressive, and disabling neurodegenerative movement disorder. Signs and symptoms begin insidiously and overlap with other neurodegenerative conditions...

Blood and cerebrospinal fluid markers in Parkinson's disease: current biomarker findings

Blood and cerebrospinal fluid markers in Parkinson's disease: current biomarker findings Claire Henchcliffe Department of Neurology, Weill Cornell Medical College, New York, NY, USA Abstract: Parkinson’s disease (PD) is a common, progressive, and disabling neurodegenerative movement disorder. Signs and symptoms begin insidiously and overlap with other neurodegenerative conditions...

Serum biomarker release patterns following alcohol septal ablation for treatment of hypertrophic cardiomyopathy

Serum biomarker release patterns following alcohol septal ablation for treatment of hypertrophic cardiomyopathy Joseph D Foley,1 Craig S Miller,2 J Darrell Sneed,1 Jeffrey L Ebersole,2 Richard J Kryscio,3 John T McDevitt,4 Charles L Campbell5 1Gill Heart Institute and Division of Cardiovascular Medicine, Department of Internal Medicine, 2Department of Oral Health Practice...

Serum biomarker release patterns following alcohol septal ablation for treatment of hypertrophic cardiomyopathy

Serum biomarker release patterns following alcohol septal ablation for treatment of hypertrophic cardiomyopathy Joseph D Foley,1 Craig S Miller,2 J Darrell Sneed,1 Jeffrey L Ebersole,2 Richard J Kryscio,3 John T McDevitt,4 Charles L Campbell5 1Gill Heart Institute and Division of Cardiovascular Medicine, Department of Internal Medicine, 2Department of Oral Health Practice...

Ion channel messenger RNA processing defects and arrhythmia

Ion channel messenger RNA processing defects and arrhythmia Anyu Zhou, Samuel C Dudley Jr Lifespan Cardiovascular Research Center, The Warren Alpert School of Medicine, Brown University, and Providence Veterans Administration Medical Center, Providence, RI, USA Abstract: Messenger RNA (mRNA) processing is an essential step for the expression of most eukaryote genes. Ion channels...