AI generated misinformation in public health PR: Combatting deepfakes in vaccine advocacy
Journal of Language, Literature, Social, and Cultural Studies, Volume 4 Number 1 (Mar 2026), p. 79-90
e-ISSN: 2986-4461
DOI: https://doi.org/10.58881/jllscs.v2i2
https://ympn.co.id/index.php/JLLSCS
AI-generated misinformation in public health PR: Combatting deepfakes
in vaccine advocacy
Presly ‘Ruke Obukoadata, PhD1, Arikoro Emmanuel2
Department of Public Relations & Advertising, Delta State
University, Abraka1
Department of Mass Communication, Delta State University,
Abraka2
1Email:
2Email:
Abstract - This study was carried out to examine the impact of AI-generated
misinformation (deepfakes) on vaccine advocacy, investigate the sources of deepfakes, and
identify factors contributing to their spread. The Elaboration Likelihood Model (ELM) was
employed to explain how people process and respond to AI-generated misinformation. A
library research method was used, involving the collection and analysis of existing data
from various secondary sources. The study revealed that social media platforms, antivaccine groups, malicious actors, and influencers are primary sources of deepfakes. It was
found that emotional appeal, personalization, vulnerabilities in media literacy, and
confirmation bias contribute to the spread of misinformation. It was concluded that the
proliferation of deepfakes has significantly eroded public trust in vaccines and health
authorities, highlighting the need for a multi-faceted approach to combat misinformation.
It is therefore recommended that social media platforms should implement robust
verification mechanisms, public health authorities should develop fact-based information
addressing emotional concerns, and the public should be educated on media literacy skills.
Keywords: AI-generated misinformation; deepfakes; public health communication;
misinformation detection; vaccine advocacy
1. Introduction
The rapid advancement of artificial intelligence (AI) technology has transformed the way information is
created, disseminated, and consumed. However, this technological progress also brings about
unprecedented challenges, particularly in the realm of public health. The proliferation of AI-generated
misinformation, including deepfakes, has become a pressing concern in vaccine advocacy. Artificial
Intelligence (AI) has rapidly transformed various sectors, including communication and public health. It is
the simulation of human intelligence processes by machines and encompasses learning, reasoning, and
self-correction (Binns, 2021). However, alongside its potential benefits, AI has also facilitated the spread of
misinformation, particularly in public health contexts. Misinformation can be described as false or
misleading information spread irrespective of intent, which can severely impact public perceptions and
This article is an open access article distributed under the terms and conditions of
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Journal of Language, Literature, Social, and Cultural Studies, Volume 4 Number 1 (Mar 2026), p. 79-90
e-ISSN: 2986-4461
DOI: https://doi.org/10.58881/jllscs.v2i2
https://ympn.co.id/index.php/JLLSCS
behaviors towards health initiatives (Nduka, 2020). Consequently, understanding the dynamics of AIgenerated misinformation is crucial for developing effective public health communication strategies.
In the realm of public health public relations (PR), effective communication is vital for fostering
trust and encouraging positive health behaviors. Public health PR efforts aim to inform and educate the
public about health issues, thereby promoting healthy practices (Gollust, 2020). However, the proliferation
of misinformation complicates these efforts. For instance, during health crises such as the COVID-19
pandemic, misinformation regarding vaccines and treatments has hindered public compliance with health
guidelines (Kperogi, 2020; Obukoadata, 2010). Thus, the relationship between public health PR and
misinformation is critical, as the latter undermines the credibility of health messages and can lead to
adverse health outcomes.
One of the most concerning manifestations of AI-driven misinformation is the emergence of
deepfakes. It refers to manipulated digital content that appears authentic, can be used to spread false
information, fuel vaccine hesitancy, and undermine public trust in health institutions. Deepfakes utilize
sophisticated algorithms to create hyper-realistic but fabricated audio and video content, making it
increasingly difficult for individuals to discern fact from fiction (Ular, 2018). This technology poses a
significant threat to public health communications, particularly in vaccine advocacy, where visual and
auditory credibility is paramount. As deepfakes can easily manipulate public sentiment and sow distrust
in health authorities, their potential to fuel vaccine hesitancy is alarming (Nwadike, 2021; Obukoadata, et
al., 2020). Thus, the intersection of AI, misinformation, and public health PR raises pressing concerns about
the integrity of health communications.
Vaccine hesitancy, characterized by reluctance or refusal to vaccinate despite the availability of
vaccines, has emerged as a significant barrier to achieving herd immunity and controlling infectious
diseases (Olajide, 2020). This hesitancy is often exacerbated by misinformation, including that propagated
through deepfake technology. For example, false narratives about vaccine safety can be amplified through
manipulated media, leading to increased public skepticism and hesitancy (Osazuwa, 2020).
The consequences of AI-generated misinformation in public health can be severe. Vaccine
misinformation, for instance, has been linked to declining vaccination rates, outbreaks of preventable
diseases, and increased mortality. As the World Health Organization (WHO) has emphasized, vaccine
misinformation is a major threat to global health security. Therefore, it is imperative to develop effective
strategies to combat AI-generated misinformation in public health, particularly in vaccine advocacy.
Consequently, addressing the role of AI-generated misinformation in vaccine advocacy is essential for
improving public health outcomes.
In light of the above relationships, this study focuses on the role of AI-generated misinformation,
particularly deepfakes, in shaping public perceptions of vaccines and the subsequent implications for
public health PR. Through examining how misinformation influences vaccine hesitancy and the
effectiveness of public health communication strategies, this research provides insights that can enhance
vaccine advocacy efforts in an increasingly complex media landscape.
The increasing sophistication and accessibility of artificial intelligence (AI) technologies have
introduced new challenges to public health communication, particularly in the realm of vaccine advocacy
(Ahmed, 2020; Bathran, 2022). Among these challenges, AI-generated misinformation, especially in the
form of deepfak (...truncated)