Will we ever have a universal anaesthetic breathing system?
Robert J. Byrick FRCPC
0
D. Keith Rose FRCPC
0
0
Department of Anaesthesia, St. Michael's Hospital
,
3~3Bond Street, Toronto, Ontario, MSB IW8
W i l l w e e v e r h a v e a u n i v e r s a l a n a e s t h e t i c breathing s y s t e m ?
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breathing and hence alveolar CO2 tensions were not
evaluated. Such factors as mask anaesthesia with an
increase in deadspace, 5 respiratory waveform
changes with various anaesthetic agents, 6 and the
effect of altering the resistance of relief valves
within the breathing system have not been
considered. The universal application of a single
breathing system requires that this technique be
equally safe for all patients when used with a
standardized FGF rate.
What are safe levels of carbon dioxide found in
inspired gases and what is the best measurement
technique for determining inspired PCO2? Humphrey
et a l . ' s conclusions are based on midstream
samples measured at the mouth. Some authors 6
have chosen to measure inspired CO2 sampled at the
carina to minimize sampling error and assess the
volume of the CO2 inspired beyond the upper
airway. Humphrey7 himself recognizes that
"determination of the point at which rebreathing becomes
clinically significant will continue to present a
problem." He has chosen to use the point at which
the minimum inspired CO2 tension reached 2 nmal-Ig
(0.3 per cent). Conway has objected to this
definition of rebreathing, s Humphrey's end-point means
that some CO2 is inhaled into the upper airway
throughout the inspiratory phase and may
participate in gas exchange. Just how much CO2 reaches
the alveoli was not determined in this study. Is this
degree of rebreathing always associated with
elevated PaCO2 levels without other factors being
altered? Before one can generalize that no
rebreathing occurs with the A_.D.E. circuit in the "A
mode" at a FGF of 50 ml'kg- ~-min- ~, more
investigation is needed.
The most efficient use of fresh gas with any
circuit during spontaneous ventilation occurs when
flows are set such that rebreathing is just detected. If
this flow equals the patient's alveolar ventilation
then all fresh gas participates in alveolar gas
exchange, none is wasted, and fractional utilization
is unity (100 per cent). In the current study, when
rebreathing was detected, Humphrey et al, l
calculated the A.D.E. utilized 73 percent of the fresh gas
(51.4---5.2ml'kg-l-min -l FGF) compared to 51
per cent for the Magill circuit (71.2 --- 6.0 ml.kg- ~.
min-I FGF).
By adding tubing for an expiratory limb and
moving the expiratory valve downstream the
functional characteristics and efficiency of Mapleson's 3
original A system appear to have been improved.
However do these lower flows and improved
fractional utilization mean increased risks or
benefits? A mean fresh gas flow value of 51.4-+ 5.2
ml.kg-~.min -~ (mean --- SD) derived from ten
patients does not guarantee that CO2 free inspired
gas nor normal minute ventilation will be obtained
when a standardized flow of 50 ml.kg -I-min -1 is
used in every patient. Even though better utilization
of fresh gas is achieved in this circuit, this standard
deviation implies that some of these healthy patients
would have been rebreathing CO2 if a FGF of only
50 ml.kg- l.min- l had been used. One must
recognize that the data imply that a FGF of 50 ml.kg -~.
min-t prevents rebreathing. This is not an absolute
guarantee, but rather an average approximation.
The rule still must be "user beware" when selecting
a FGF rate for spontaneous breathing.
What are the potential risks of using a convertible
"universal" anaesthetic breathing system?
Problems such as errors in lever placement could be
avoided with experience. However, how is the "A
mode" coaxial system checked for leaks? Since the
reservoir bag is on the inspiratory side the Pethick
test used for modified "D" systems will not apply.
Manual ventilation can only be achieved in the "A
mode," yet the exact fresh gas flow requirements,
the amount of ventilation and other limitations have
not been fully defined.
Humphrey's ingenuity and progress in
simplifying the more complex dual lever system should be
applauded. He has eliminated several sources of
error and reduced the complexity of the system. As
with other systems only in time will all problems be
defined. In Canada there are no minimum safe
standards of either function or structure of
anaesthetic breathing systems. Canadian Standards
Association (C.S.A.) approval is not necessary prior to
marketing new breathing systems. C.S.A.
guidelines for breathing systems are to be released in the
near future. The Canadian Anaesthetists' Society
and its members must address this issue to ensure
elimination of faults before new equipment is used
in Canada as we do for new pharmaceutical
products. To state that technology should be made as
safe as possible helps very little. The safety of
machines can almost always be improved but, at
some point, the price of safety is increasing
complexity and cost.
A major message stressed by Humphrey et al. 1 is
that anaesthetists should choose their breathing
system and FGF as carefully as they choose their
anaesthetic drugs. The Humphrey A.D.E. system
will be useful only if the clinical anaesthetist
understands the functional characteristics of both
the A and D mode and the limitations are fully
documented.
A u r i o n s - n o u s un
s y s t r m e de circuit
anesthrsique
universel?
Dans ce numfro du Journal, Humphrey et collrgues
drcrivent une version du circuit anesthrsique
A.D.E.t'2 qui serait scion eux optimale pour tous
les patients. Humphrey et al. ont drmontr6 que le
syst~me "A.D.E. universel b. bas flow" fonctionne
comme un syst~me D modifi6 (classification de
Mapleson3) ou comme un circuit de Bain pour la
ventilation contrrlre et lors de la mise en marche
d'un interrupteur unique comme un syst~me A de
Mapleson (ou circuit Lack) pour la respiration
spontanre.
Les donnres prrsentes sont en accord avec les
6tudes prralables utilisant le mode D. En ventilation
contrrlre (partie H)2 et mode D (A.D.E.) la PCO2
artrrielle de dix patients 6tait prrvisible avec un riot
de gaz frais de 70ml.kg-~.min -L et un volume
courant de 10 ml'kg-1 et une frrquence respiratoire
de 12 ~t 15/minute (i.e., ia ventilation contrrlre).
(...truncated)