Impact of Pharmacist-Led Education on Prescribing Habits for Acute Treatment of Suspected Sexually Transmitted Infections (STIs) in an Academic Medical Center Emergency Department (ED)

1906. Impact of Pharmacist-Led Education on Prescribing Habits for Acute Treatment of Suspected Sexually Transmitted Infections (STIs) in an Academic Medical Center Emergency Department (ED) Jennifer Anthone, PharmD1,2,3; Ann Cabri, PharmD Candidate1,3; Ryan Walters, PhD2; Christopher Destache, PharmD2,3; Renuga Vivekanandan, MD1,2; 1CHI Health Creighton University Medical Center, Omaha, Nebraska; 2Medicine, Creighton University School of Medicine, Omaha, Nebraska; 3Creighton University School of Pharmacy and Health Professions, Omaha, Nebraska Session: 224. Antibiotic Stewardship: Outpatient and ED Saturday, October 29, 2016: 12:30 PM Background. Implementation of a pharmacist-managed culture review follow-up process in our hospital’s ED was initiated in November 2013. Post-implementation assessment revealed areas for improvement, including the acute treatment of suspected STIs. We sought to evaluate the impact of pharmacist-led education on CDC guideline adherence for acute treatment of suspected STIs in the ED pre- and post-education. We also looked to increase on-site, directly observed therapy and improve confirmed treatment for patients with positive test results. Methods. This quality improvement project included all patients who presented to the ED and met CDC criteria for symptomatic STI. Following ED discharge, patient electronic medical records were reviewed retrospectively to assess for symptomatology, antimicrobials administered in the ED, and discharge prescriptions to determine prescribing compliance with CDC guidelines. STI education was conducted by the antimicrobial stewardship pharmacist at a monthly ED provider meeting and included recommendations from the CDC for the acute treatment of urethritis and cervicitis. Pre-education and post-education data was analyzed using SAS v. 9.4 and statistical significance was indicated by a p value < 0.05. Results. A total of 280 patients were included in this project for assessment ( preeducation = 112, post-education = 168). After completion of ED provider education, a statistically significant increase was seen in CDC compliant antimicrobial prescribing in our ED for acute treatment of suspected STIs (17.9% versus 44.1%, p < 0.05). There was also a significant increase in the percentage of on-site, directly observed therapy received in the ED (15.2% versus 42.3%, p < 0.05). In addition, it was confirmed that significantly more patients with positive test results ultimately received appropriate treatment post education (36.4% versus 75%, p < 0.05). Follow-up education was provided to ED providers regarding these results to further enhance compliance. Conclusion. Education of ED prescribers significantly increased prescriber compliance with CDC guidelines for acute treatment and administration of antimicrobial therapy on-site in the ED for suspected STIs and confirmed treatment among patients with positive test results. Disclosures. All authors: No reported disclosures Poster Abstracts • OFID 2016:3 (Suppl 1) • S515  (...truncated)