Retinal detachments are ophthalmic emergencies given their potential to become a permanently blinding disorder if left untreated. This review will outline the history, pathogenesis, clinical presentation, and current and future management of retinal detachments.
Die Studie beschreibt erstmals Forschungen der DDR-Staatssicherheit zu Polygraphen und Stimmanalysatoren sowie deren konspirativen Einsatz. Anhand von Stasiakten wird gezeigt, dass der sogenannte Lügendetektor auch in der DDR angewandt wurde. Zwar schätzten die MfS-Oberen etwa bis Ende der 1960er Jahre psychophysiologische Tests mit dem Polygraphen als fragwürdig und ethisch...
Social media is a significant source of information on health-related topics and neurodevelopmental disorders such as autism spectrum disorder (ASD). The public perception of ASD, as reflected on social media, can raise awareness but also increase stigma. This study examined ASD portrayal on TikTok, focusing on neurodiversity, content themes, creator identities, and the depiction...
Big data collected in large international cooperations allow validation of findings from traditional national patient cohorts for proving consistency. In this study we analyzed outcomes and phenotypic features of TP53-mutated chronic myelomonocytic leukemia (CMML) patients in the Austrian biodatabase for CMML (ABCMML; n = 322) and in the international platform cBIOPORTAL (n = 399...
Intravitreal injections have revolutionized the treatment of various sight-threatening diseases of the posterior segment of the eye. Initially explored for treatment of bacterial endophthalmitis, intravitreal injections rapidly expanded to combat retinal vascular disease in particular. Especially anti-vascular endothelial growth factor agents have emerged as a cornerstone of...
Given how the diagnosis and management of many ocular and, most specifically, retinal diseases heavily rely on various imaging modalities, the introduction of artificial intelligence (AI) into this field has been a logical, inevitable, and successful development in recent decades. The field of retinal diseases has practically become a showcase for the use of AI in medicine. In...
Fragility fractures caused by osteoporosis, the most common metabolic bone disease, place a significant burden on affected individuals and impose substantial economic costs. A fragility fracture implies an imminent elevated risk for subsequent fractures, particularly in the short term. Therefore, osteoporosis must be addressed in the event of a sentinel fracture, if not already...
Despite extensive diagnostic efforts, the etiology of stroke remains unclear in up to 30% of patients. Mechanical thrombectomy (MT) potentially enhances etiological determination by (immuno)histological analysis of retrieved thrombotic material. In this monocentric exploratory study, clots from 200 patients undergoing MT were investigated by hematoxylin and eosin, CD3, and CD45...
Als im 15. Jahrhundert neben den bisherigen küstennahen Seefahrten mit leicht erreichbarer frischer Kost die oft jahrelangen Seereisen nur mit konservierten Lebensmitteln (Fische, Salzfleisch, Zwieback) unternommen wurden, trat nach wenigen Wochen bei den Besatzungen eine oft tödliche Krankheit mit Hinfälligkeit, Ausfall der Zähne und fürchterlichem Gestank aus dem Mund auf. Bald...
There are few studies that have analyzed the characteristics of hypercalcemia in hospitalized oncological patients. Our objectives were to describe the clinical characteristics of hospitalized patients with paraneoplastic hypercalcemia and to identify prognostic variables for mortality. This was an observational, longitudinal, retrospective, and bicentric study. It included adult...
RN Braun observed that frequencies of health disorders in general practice are so consistent that he called his discovery “Case Distribution Law”. Our study compares morbidity data from methodologically similar surveys in primary care practices over a period of fifty years. Frequency ranks were determined for each observation period and the first 150 ranks were compared with...
Umbilical venous catheters (UVCs) are often used in preterm infants. Their use is associated with complications (infections, clot formation, organ injury). Very preterm infants with acquired bloodstream infection are at a higher risk for death and important morbidities (e.g., adverse neurodevelopmental outcomes). It is standard clinical practice to remove UVCs in the first days...
Over the past decade, the European Society for Paediatric Gastroenterology, Hepatology and Nutrition (ESPGHAN) proposed the option of diagnosing coeliac disease (CD) in children without duodenal biopsy. The aim of our study was to assess the diagnostic approach in newly diagnosed children with CD in Slovenia. In this prospective study, Slovenian paediatric gastroenterologists...
Spinal cord injuries (SCIs) are a global concern, annually affecting hundreds of thousands of individuals. Among these cases, incomplete SCIs, allowing some muscle activity below the injury, pose unique challenges. This case study focuses on a 55-year-old male with a moderate incomplete SCI (AIS-D). After initial treatments and pharmaceutical antispastic therapy, a novel...
In this publication 125 years after the violent death of the famous Empress Elisabeth (1837–1898) of Austria, known as Sisi, a modern evaluation as well as valuation will be presented. The day after her assassination by the young anarchist Luigi Lucheni using a file, a partial autopsy was performed to find out the exact cause of death—a pericardial tamponade. The complete...
A 72-year-old male with dementia and Parkinson’s disease presented at the otorhinolaryngology outpatient clinic with acute dysphagia. A chest x‑ray showed a dental prosthesis in the upper esophagus, which was subsequently extracted via rigid esophagoscopy. Due to suspected esophageal perforation on postoperative CT, a cervical approach to the esophagus and flexible esophagoscopy...
Non-specific low back pain (NLBP) is a common and clinically significant condition with substantial socioeconomic implications. Whole-body vibration therapy (WBVT) has shown effectiveness in improving pain and sensorimotor function (e.g., in osteoporosis) in previous studies. However, studies had heterogeneous settings. The aim of this study was to assess the effects of WBVT on...
Non-specific low back pain is a common and clinically significant condition with substantial socioeconomic implications. Pulsed electromagnetic field (PEMF) therapy has shown benefits in pain reduction and improvement of physical function in patients with pain-associated disorders like osteoarthritis. However, studies had heterogeneous settings. The aim of this study was to...
Es ist in der Geschichtsforschung seit Langem bekannt, dass der Habsburger Kaiser Maximilian II (1527–1576) zeitlebens unter Herzbeschwerden litt. Zahlreiche Biografen erwähnen diesen Umstand. Seine Krankengeschichte und selbst die Ergebnisse der Obduktion seiner Leiche sind überliefert. Nur unzureichend untersucht ist dagegen, wie Maximilians Ärzte dessen häufig als „Herzzittern...