Journal of Genetics

This is the oldest English language journal in genetics. Founded by W. Bateson and R. C. Punnett in 1910, the Journal of Genetics was later edited by J. B. S. ...

List of Papers (Total 61)

Inheritance and molecular tagging of genes introgressed from Gossypium arboreum to G. hirsutum for leafhopper tolerance

Cotton cultivation is conquered by transgenic Bt upland cotton hybrids in India. Bt gene does not provide resistance against sucking insect pests. Due to the inherent vulnerability of extant Bt cotton hybrids to sap-sucking insect pests including leafhopper, upland cotton cultivation is seriously threatened by surging populations of these pests. Consistent and extensive screening...

Transformation to telephonic genetic counselling during SARS-CoV-2 pandemic: challenges and suggested protocol in Indian scenario

Genetic counselling (GC) is a process of communicating and educating patients and/or their family members diagnosed with genetic abnormalities. Ideally, GC is offered in-person, physical presence of both the counselee and the counsellor. However, COVID-19 pandemic and new norms of social distancing precluded undertaking GCs. In the wake of this, Genetic Research Centre at ICMR...

Molecular docking studies of Indian variants of pathophysiological proteins of SARS-CoV-2 with selected drug candidates

SARS-CoV-2 pandemic has recently made the entire world come to a standstill. The number of cases in the world, especially India, have been increasing exponentially. The need of the hour is to assimilate as much data as possible to fast track the pipeline of bringing in new therapeutic tools against this fatal virus. In this brief communication, we aim to throw light on the...

Contributions of human ACE2 and TMPRSS2 in determining host–pathogen interaction of COVID-19

Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) infection is at present an emerging global public health crisis. Angiotensin converting enzyme 2 (ACE2) and trans-membrane protease serine 2 (TMPRSS2) are the two major host factors that contribute to the virulence of SARS-CoV-2 and pathogenesis of coronavirus disease-19 (COVID-19). Transmission of SARS-CoV-2 from...

Age-related gene expression alterations by SARS-CoV-2 infection contribute to poor prognosis in elderly

The ongoing pandemic caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has affected millions of people worldwide and with notable heterogeneity in its clinical presentation. Probability of contracting this highly contagious infection is similar across age groups but disease severity and fatality among aged patients with or without comorbidities are reportedly...

Towards a more healthy conservation paradigm: integrating disease and molecular ecology to aid biological conservation †

Parasites, and the diseases they cause, are important from an ecological and evolutionary perspective because they can negatively affect host fitness and can regulate host populations. Consequently, conservation biology has long recognized the vital role that parasites can play in the process of species endangerment and recovery. However, we are only beginning to understand how...

Variability of the EG95 antigen-coding gene of Echinococcus granulosus in animal and human origin: implications for vaccine development

In the present study, the genetic variability of the EG95 protein-coding gene in several animal and human isolates of Echinococcus granulosus was investigated. A total of 24 isolates collected from cattle, buffalo, sheep, goat, dog and man were amplified by Eg95-coding gene-specific primers. From the generated sequence information, a conceptual amino acid sequence was deduced...