To compare the effectiveness and safety of different acupuncture-related therapies combined with pharmacotherapies for treating symptomatic endometriosis. A pre-defined search strategy was conducted across eight databases (Chinese Biomedical Literature Service System, China National Knowledge Infrastructure, Wanfang Data Knowledge Service Platform, China Science and Technology...
The relationship of the first-trimester triglyceride-glucose (TyG) index with GDM (gestational diabetes mellitus) and other adverse pregnancy outcomes has yet to be fully understood. This study aims to investigate the relationship between the first-trimester TyG index and the risk of adverse pregnancy outcomes in pregnant women. The data for the retrospective cohort study were...
Evidence shows that twin pregnancy is associated with increased adverse outcomes, including stillbirth. The present study aimed to investigate the global prevalence of stillbirth among fetuses resulting from twin pregnancies through a systematic review and meta-analysis. To identify relevant studies, we adhered to the Preferred Reporting Items for Systematic Reviews and Meta...
Tinidazole shows potential as a first-line treatment for bacterial vaginosis (BV). However, its superiority to metronidazole remains uncertain. Therefore, this meta-analysis compares tinidazole versus metronidazole in patients with BV. We systematically searched PubMed, Embase and Cochrane for studies comparing tinidazole and metronidazole in patients with BV. Statistical...
To offer more effective strategies by classification of non-reportable results for physicians to manage those pregnancies. From July 2022 to May 2024, a total of 14,073 prenatal cell-free DNA (cfDNA) tests were performed by massively parallel sequencing (MPS) in our genetic laboratory and 52 cases received non-reportable results caused by different reasons. Chi-square analysis...
The aim of the study is to review the clinical characteristics and risk factors that influence the timing of diagnosis and rupture of interstitial pregnancy, and to evaluate the outcomes of interstitial heterotopic pregnancies after ipsilateral tubal surgery. A retrospective statistical analysis was performed on the case data of patients with interstitial pregnancy who met the...
To investigate whether the number of oocytes retrieved after controlled ovarian stimulation (COS) for fertility preservation (FP) can be predicted using serum anti-Müllerian hormone (AMH) levels in adolescent and young adult (AYA) women. This is a retrospective cohort study in a large university-affiliated fertility center. AYA women aged 11 to 25 years received COS using...
Mitral stenosis (MS) is recognized as one of the most common cardiovascular diseases during pregnancy and can result in adverse outcomes including maternal and fetal mortality if not diagnosed and treated in a timely manner. This study aimed to investigate the pregnancy outcomes of women with MS who were treated at the cardio-obstetric clinic in Alzahra Hospital, Isfahan, from...
Whether SDF (sperm DNA fragmentation) influences embryo development and the clinical outcomes of assisted reproductive technology (ART) cycles remains controversial. Oocytes derived from women of different ages have varying abilities to repair SDF. This study aimed to explore the correlation between SDF and the morphokinetic parameters of embryos during intracytoplasmic sperm...
Elevated progesterone (P4) has emerged as a cofounder for embryo quality and recently been investigated in blastocyst aneuploidy rates. In this context, we explored the prevalence of aneuploidy in blastocysts generated from donated eggs according to P4 levels on trigger’s day. This retrospective cohort study analyzed data from intracytoplasmic sperm injection (ICSI) cycles using...
Information on the impact of Progestin-primed ovarian stimulation (PPOS) protocol on embryo euploid status and preimplantation genetic testing for aneuploidy (PGT-A) outcomes is limited compared with other ovarian stimulation protocols. We conducted a retrospective cohort study and a meta-analysis to evaluate the application value of the PPOS protocol in PGT-A cycles. In the...
Polycystic Ovary Syndrome (PCOS) is a multifaceted endocrine-metabolic condition affecting around 5–15% of women globally. Despite its prevalence and diverse impact, the psychological aspect of PCOS is often underestimated in clinical settings, leading to significant distress among affected individuals. This study aimed to explore the extent of body image perception disorders...
Due to increasing life expectancy and demographic trends in recent years, the specific needs of elderly patients have gained more and more attendance. The aim of this study is to determine the impact of adjuvant chemotherapy on health-related life satisfaction of elderly breast cancer patients while considering the conditions of comorbidities and global health status. All breast...
Vesicovaginal fistula (VVF) refers to an abnormal communication between the bladder and vagina, leading to uncontrolled leakage of urine from the vagina. This study aimed to assess the efficacy and safety of robot-assisted laparoscopic VVF repair with a “rainbow-shaped” peritoneal flap. A retrospective analysis was conducted on 15 patients who underwent robot-assisted VVF repair...
To evaluate the effect of intrauterine platelet-rich plasma (PRP) treatment on frozen–thawed embryo transfer (FET) cycles in patients with recurrent implantation failure. The study group consisted of 150 patients. The patients were grouped only as those with thin endometria, those with recurrent implantation failure (RIF), and those with both thin endometria and RIF. All...
GnRH-a is commonly used in the luteal phase for pituitary down-regulation during in-vitro fertilization (IVF). There is an ineluctable risk of spontaneous pregnancy for infertile couples who lack the use of contraception during the luteal phase down-regulation before IVF treatment. However, it is unclear whether exposure to GnRH-a affects clinical pregnancy outcomes. A single...
To evaluate the live birth rate (LBR) following donor frozen embryo transfer (dFET) of preimplantation genetic testing for aneuploidy (PGT-A) versus untested donor embryos, stratified by blastocyst morphologic grade (MG). This was a retrospective cohort study of 146 patients undergoing dFET of a single euploid blastocyst from fresh or frozen oocytes using PGT-A compared to age...
To evaluate risk factors in patients presenting with postpartum hemorrhage (PPH) associated with severe blood loss (BL), surgical intervention or peripartum hysterectomy. This retrospective cohort study included all patients who gave birth at the Hannover Medical School between January 2013 and August 2022 with PPH, defined as BL ≥ 500 ml after vaginal delivery and ≥ 1000 ml...
The aim of this study was to evaluate the average latency to delivery, obstetric outcomes and neonatal survival in pregnancies complicated by preterm premature rupture of membranes (PPROM) before 32 weeks. A retrospective study was conducted on pregnant women admitted for PPROM before 32 weeks. Patients were categorized into three groups based on gestational age (GA) at PPROM...
We aimed to retrospectively analyze the efficacy and safety of autologous bone marrow mesenchymal stem cells (BM-MSCs) as adjuvant therapy for intrauterine adhesion (IUA) and endometrial repair. Patients enrolled at Shengjing Hospital Affiliated to China Medical University from January 2017 to January 2020 for the treatment of infertility who diagnosed with recurrent IUA as...
Sonographically guided core needle biopsy (CNB) is a well-established tool for diagnosing breast lesions. Preoperative estrogen receptor (ER), progesterone receptor (PR), and HER2-receptor status are essential for a personalized treatment approach. We evaluated the concordance of the hormone- and HER2-receptor status between the CNB and the surgical specimen to determine the...
Laparoscopic myomectomy is one of the preferred surgical treatments for symptomatic uterine fibroids. This study aimed to compare the effects of laparoscopic myomectomy with temporary uterine artery occlusion (TUAO), permanent uterine artery occlusion (PUAO), and vasopressin injection (VPI) on ovarian reserve in women with symptomatic uterine leiomyomas. This randomized clinical...