Human Reproduction

Human Reproduction features full-length, peer-reviewed papers reporting original research, clinical case histories, as well as opinions and debates on topical issues.Papers published cover the scientific and medical aspects of reproductive physiology and pathology, endocrinology, andrology, gonad function, gametogenesis, fertilization, embryo development, implantation, pregnancy, genetics, genetic diagnosis, oncology, infectious disease, surgery, contraception, infertility treatment, psychology, ethics and social issues.

List of Papers (Total 9,882)

Recurrent miscarriage in translocation carriers: no differences in clinical characteristics between couples who accept and couples who decline PGD

STUDY QUESTION Do clinical characteristics of recurrent miscarriage couples with a chromosomal abnormality and who opt for PGD differ from couples that decline PGD after extensive genetic counselling?

Targeting high mobility group box protein 1 ameliorates testicular inflammation in experimental autoimmune orchitis

STUDY QUESTION Does high mobility group box protein 1 (HMGB1) regulate inflammatory reactions in a rat model of experimental autoimmune orchitis (EAO)?

Endometriosis also affects the decidua in contact with the fetal membranes during pregnancy

STUDY QUESTION Are the fetal membranes of women affected with endometriosis similar to those from disease-free women?

Surrogate mothers 10 years on: a longitudinal study of psychological well-being and relationships with the parents and child

STUDY QUESTION How do the psychological health and experiences of surrogate mothers change from 1 year to 10 years following the birth of the surrogacy child?

Intentions and attitudes towards parenthood and fertility awareness among Chinese university students in Hong Kong: a comparison with Western samples

STUDY QUESTION What are the levels of awareness regarding female fertility and the intentions and attitudes towards parenthood among Chinese university students in Hong Kong compared with their counterparts in the West?

Fertility awareness online: the efficacy of a fertility education website in increasing knowledge and changing fertility beliefs

STUDY QUESTION How effective is online education in increasing knowledge of fertility and assisted reproductive technologies (ART), and changing beliefs about the timing of parenthood?

Assisted reproduction involving gestational surrogacy: an analysis of the medical, psychosocial and legal issues: experience from a large surrogacy program

STUDY QUESTION What are the medical, psychosocial and legal aspects of gestational surrogacy (GS), including pregnancy outcomes and complications, in a large series?

Does oocyte banking for anticipated gamete exhaustion influence future relational and reproductive choices? A follow-up of bankers and non-bankers

STUDY QUESTION What is the nature of the relational status, reproductive choices and possible regret of a pioneer cohort of women that either considered or actually performed oocyte banking for anticipated gamete exhaustion (AGE)?.

Patient preference for a long-acting recombinant FSH product in ovarian hyperstimulation in IVF: a discrete choice experiment

STUDY QUESTION What factors or attributes of a long-acting recombinant FSH (rFSH) or daily-administrated rFSH influence women's preferences IVF?

Prevalence of chronic endometritis in repeated unexplained implantation failure and the IVF success rate after antibiotic therapy

STUDY QUESTION What is the prevalence of chronic endometritis (CE) in women with repeated unexplained implantation failure (RIF) at IVF, and how does antibiotic treatment affect the reproductive outcome?

Endometriotic ovarian cysts do not negatively affect the rate of spontaneous ovulation

STUDY QUESTION Do endometriotic ovarian cysts influence the rate of spontaneous ovulation?

The use of morphokinetics as a predictor of implantation: a multicentric study to define and validate an algorithm for embryo selection

STUDY QUESTION Can we use morphokinetic markers to select the embryos most likely to implant and are the results likely to be consistent across different clinics?

No benefit of culturing embryos in a closed system compared with a conventional incubator in terms of number of good quality embryos: results from an RCT

STUDY QUESTION Does culture in a closed system result in an increased number of good quality embryos (GQE) on Day 2 compared with culture in a conventional system?

Risk for borderline ovarian tumours after exposure to fertility drugs: results of a population-based cohort study

STUDY QUESTION Do fertility drugs increase the risk for borderline ovarian tumours, overall and according to histological subtype?

Time to second abortion or continued pregnancy following a first abortion: a retrospective cohort study

STUDY QUESTION What proportions of women have a second abortion or continued pregnancy within 12–46 months of a first abortion?

Cervical conization doubles the risk of preterm and very preterm birth in assisted reproductive technology twin pregnancies

STUDY QUESTION Does cervical conization add an additional risk of preterm birth (PTB) in assisted reproduction technology (ART) singleton and twin pregnancies?

Male experiences of unintended pregnancy: characteristics and prevalence

STUDY QUESTION What are the characteristics and circumstances of pregnancies men report as unintended in France?

Ovarian response prediction in GnRH antagonist treatment for IVF using anti-Müllerian hormone

STUDY QUESTION What is the clinical value of anti-Müllerian hormone (AMH) for the prediction of high or low ovarian response in controlled ovarian stimulation for IVF using GnRH antagonist treatment?

NLRP7 and KHDC3L, the two maternal-effect proteins responsible for recurrent hydatidiform moles, co-localize to the oocyte cytoskeleton

STUDY QUESTION What is the subcellular localization in human oocytes and preimplantation embryos, of the two maternal-effect proteins, NLRP7 and KHDC3L, responsible for recurrent hydatidiform moles (RHMs)?

Overlap of proteomics biomarkers between women with pre-eclampsia and PCOS: a systematic review and biomarker database integration

STUDY QUESTION Do any proteomic biomarkers previously identified for pre-eclampsia (PE) overlap with those identified in women with polycystic ovary syndrome (PCOS).

Human embryos from overweight and obese women display phenotypic and metabolic abnormalities

STUDY QUESTION Is the developmental timing and metabolic regulation disrupted in embryos from overweight or obese women?

Expectations and experiences of gamete donors and donor-conceived adults searching for genetic relatives using DNA linking through a voluntary register

STUDY QUESTION What are the experiences of donor-conceived adults and donors who are searching for a genetic link through the use of a DNA-based voluntary register service?