Malaria remains one of the major public health problems both globally and in Tanzania. In addition to existing malaria control interventions, the country plans to introduce larviciding in its efforts towards malaria control and elimination. To guide a possible national upscaling of the intervention, a pilot larviciding study using biolarvicides produced in-country was implemented...
Zanzibar has made significant progress in malaria control reaching a population prevalence of around 1% with programme-led interventions. Nevertheless, malaria infections persist in people with no recent travel history implying locally acquired infections. Understanding risk factors of local transmission is crucial to refine elimination strategies. From May 2017 to October 2018...
Malaria remains a major public health challenge in Brazil, particularly in the Amazon region, where over 90% of cases occur. Indigenous populations, such as the Yanomami, are disproportionately affected due to geographic isolation and environmental vulnerabilities. Despite logistical challenges in remote areas entomological surveillance is essential for developing effective...
Rapid Diagnostic Tests (RDT) have become an essential tool for the control of malaria worldwide. Their simplicity of use and their reliability make them ideal for the diagnosis of malaria in endemic areas. Numerous brands are now available on the market. In South East Asia, where both Plasmodium falciparum and Plasmodium vivax are prevalent, the Abbott-Bioline™ Malaria Ag Pf/Pv...
Despite evidence that most child malaria deaths occur at home shortly after symptom onset, receiving timely malaria treatment remains a significant challenge. Timely malaria treatment, defined as early diagnosis and prompt administration of appropriate anti-malarial medication within 24 h of symptom onset, is crucial for reducing mortality. However, factors influencing timely...
Malaria remains a major public health challenge in sub-Saharan Africa, accounting for approximately 95 percent of global malaria deaths despite extensive interventions. Significant disparities persist in disease burden across countries, with some achieving remarkable progress while others experiencing persistently high transmission rates, suggesting factors beyond resource...
The World Health Organization (WHO) recommends the use of malaria vaccines for the prevention of Plasmodium falciparum malaria in moderate to high transmission areas, administered in a 4-dose schedule in children from 5 months of age. The vaccine is a ground-breaking new tool to add to the existing package of recommended malaria interventions to reduce malaria morbidity and...
Over the years, malaria has remained a significant public health concern, particularly among children under five, with sub-Saharan Africa (SSA) bearing the greatest burden due to its high morbidity and mortality rates. Despite the increasing number of cases among this vulnerable age group in Nandom Municipality, there is a paucity of information on the prevalence and associated...
Undernutrition and malaria remain major global public health challenges. The relationship between nutritional status and malaria infection is complex. Better understanding of their association is needed to improve prevention and control of these health conditions. Undernutrition can be assessed by evaluating nutrient intake (macronutrient and micronutrient intake) measured...
The National Framework for Malaria Elimination, formulated in 2016, aims to eliminate malaria in India by 2030, focusing on the districts as the strategic units for planning and implementing intervention measures. In this study, the spatial distribution of malaria hotspots was investigated and the significant covariates were identified that are potentially influencing its...
Malaria continues to pose a significant public health challenge for pregnant women in Ethiopia. This study explores the facilitators and barriers influencing malaria prevention and treatment services to this vulnerable group, emphasizing systemic, policy, and community-level factors within Ethiopia’s healthcare framework. A qualitative study engaged 49 multi-level stakeholders in...
Malaria continues to be a major disease burden affecting all ages. The WHO in 2012 introduced the test, treat and track (T3) policy for malaria management in endemic settings. All malaria suspected conditions are to be confirmed by test and treatment initiated with recommended artemisinin-based combination therapy (ACT) and treatment outcomes monitored over the course of the...
Recurrent events of infectious diseases are common and the subject of analyses in many clinical studies. A proper understanding of disease occurrence over time within a cohort provides a basis for study planning and sample size estimation. This study mathematically describes the recurrence of malaria in a malaria-naïve cohort and highlights the necessary assumptions to inform...
Malaria remains the leading cause of morbidity in Guinea. Early diagnosis of malaria infections and prompt administration of appropriate treatment are two essential elements in reducing severe morbidity and mortality associated with malaria infection. This study aims to identify how community norms can shape caretakers’ care-seeking behavior for fever in children under five in...
Despite the ongoing control and elimination efforts, malaria continues to impose a substantial burden on healthcare systems and communities in Ethiopia. Understanding its epidemiology and identifying associated factors are essential for targeted interventions. The present study thus aimed to assess malaria prevalence and associated factors among febrile patients in selected...
Artemisinin-based combination therapy (ACT) has been first-line treatment for uncomplicated malaria in sub-Saharan Africa for over two decades. However, emerging artemisinin partial resistance threatens efficacy. Multiple first-line treatments (MFTs) represent a proposed mitigation strategy, though associated health systems challenges remain unknown. This study evaluated health...
Malaria remains a major public health challenge in Zimbabwe, reporting the highest prevalence in Manicaland Province, where indigenous health practices and religious beliefs influence healthcare-seeking behaviours. Understanding the interplay between biomedical and traditional approaches is essential for designing culturally sensitive malaria control strategies. The study...
Vector-borne diseases remain a major global health problem, mostly in tropical and subtropical areas. Effective vector control is crucial for controlling vector borne diseases (VBDs). Over the years various vector control tools and strategies have been employed globally. However, the recent challenges including insecticide-resistant, alterations in vector behaviour, and non...
Despite malaria control efforts, schoolchildren continue to exhibit high malaria prevalence. While multiple studies report varying malaria prevalence among schoolchildren across Africa, there is an evidence gap in comparing malaria prevalence across urban, peri-urban and rural settings, particularly in the context of changing transmission dynamics due to Anopheles stephensi...
Malaria remains a major public health challenge, particularly in sub-Saharan Africa, where women of reproductive age are especially vulnerable during pregnancy and childbirth. To identify key predictors and improve predictive accuracy, machine learning algorithms such as Random Forest were applied, along with SHAP analysis, to a large multi-country DHS dataset, with class...
Effective malaria control in under-five children depends on caregivers seeking timely medical care. However, despite available healthcare services, many caregivers do not utilize health facilities, undermining malaria control efforts. This study assessed care-seeking behaviour of caregivers for suspected malaria in under-five children and associated factors in a southwest state...
Malaria remains a major public health challenge in Nigeria with children under five years of age and pregnant women possessing the highest risk. Preventive efforts including indoor residual spraying (IRS) and insecticide-treated nets (ITN) have been implemented over the years but issues such as limited funding, low net coverage, and cultural barriers have hindered progress. This...
Malaria is one of the leading causes of morbidity and mortality in Nigeria. Distribution of insecticide-treated nets (ITNs) is an important vector control strategy. In 2022, despite security challenges and COVID-19 restrictions, an ITN distribution was implemented in Anambra state. This paper describes the adaptations made to the ITN distribution campaign to ensure the safety of...
Malaria in pregnancy (MiP) is responsible for several maternal and neonatal complications. Despite the renewed dedication towards elimination and eradication, it is still endemic in Ghana. Although previous studies have examined MiP from clinical or epidemiological standpoints, gaps remain in understanding the interactions between determinants of transmission. This study examined...
Widespread Insecticide resistance among malaria vector populations poses a significant threat to the efficacy of current vector control strategies. This highlights the urgent need for innovative approaches that integrate existing tools with those under development. The primary objective of this study was to characterize the malaria epidemiological profile in the Korhogo region...