Human Reproduction

Effectiveness of lifestyle intervention in subgroups of obese infertile women: a subgroup analysis of a RCT†

Embryo donation and understanding of kinship: the impact of law and policy

STUDY QUESTION What is the impact of law and policy upon the experience of embryo donation for reproductive use?

Contraceptive sales in the setting of the Zika virus epidemic

STUDY QUESTION Has there been any influence of the Zika virus (ZIKV) outbreak on the sales of contraceptive methods in Brazil?

Endothelin-1 down-regulates matrix metalloproteinase 14 and 15 expression in human first trimester trophoblasts via endothelin receptor type B

STUDY QUESTION Does endothelin-1 (ET-1) regulate matrix metalloproteinase (MMP) 14 and 15 production and invasion of human first trimester trophoblasts?

Causes of male infertility: a 9-year prospective monocentre study on 1737 patients with reduced total sperm counts

STUDY QUESTION What are the primary causes of severe male factor infertility?

Influence of follicle stage on artificial ovary outcome using fibrin as a matrix

Semen quality of young adult ICSI offspring: the first results

STUDY QUESTION What is the semen quality of young adult men who were conceived 18–22 years ago by ICSI for male infertility?

Consensus on Recording Deep Endometriosis Surgery: the CORDES statement†

Prenatal paracetamol exposure is associated with shorter anogenital distance in male infants

STUDY QUESTION What is the relationship between maternal paracetamol intake during the masculinisation programming window (MPW, 8–14 weeks of gestation) and male infant anogenital distance (AGD), a biomarker for androgen action during the MPW?

Extended use up to 5 years of the etonogestrel-releasing subdermal contraceptive implant: comparison to levonorgestrel-releasing subdermal implant

STUDY QUESTION Is it possible to extend the use of the 3-year one-rod etonogestrel (ENG)-releasing subdermal contraceptive implant to 5 years?

Assessment of ‘one-step’ versus ‘sequential’ embryo culture conditions through embryonic genome methylation and hydroxymethylation changes

STUDY QUESTION In comparison to in vivo development, how do different conditions of in vitro culture (‘one step’ versus ‘sequential medium’) impact DNA methylation and hydroxymethylation in preimplantation embryos?

Length of FMR1 repeat alleles within the normal range does not substantially affect the risk of early menopause

STUDY QUESTION Is the length of FMR1 repeat alleles within the normal range associated with the risk of early menopause?

Endometriomas and deep infiltrating endometriosis in adulthood are strongly associated with anogenital distance, a biomarker for prenatal hormonal environment

STUDY QUESTION Is the length of the anogenital distance (AGD), a biomarker of the in-utero prenatal hormonal environment, associated with the presence of endometriomas and deep infiltrating endometriosis (DIE)?

Characteristics of histologically confirmed endometriosis in cynomolgus monkeys

STUDY QUESTION What are the characteristics of spontaneous endometriosis in cynomolgus monkeys?

Development of a generally applicable morphokinetic algorithm capable of predicting the implantation potential of embryos transferred on Day 3

STUDY QUESTION Can a generally applicable morphokinetic algorithm suitable for Day 3 transfers of time-lapse monitored embryos originating from different culture conditions and fertilization methods be developed for the purpose of supporting the embryologist's decision on which embryo to transfer back to the patient in assisted reproduction?

Influence of embryo culture medium (G5 and HTF) on pregnancy and perinatal outcome after IVF: a multicenter RCT

STUDY QUESTION Does embryo culture medium influence pregnancy and perinatal outcome in IVF?

Time to take human embryo culture seriously†

STUDY QUESTION Is it important that end-users know the composition of human embryo culture media?

Peanut butter

Prevalence of infertility and help seeking among 15 000 women and men

STUDY QUESTION What is the prevalence of infertility and of help seeking among women and men in Britain?

Online sperm donation: a survey of the demographic characteristics, motivations, preferences and experiences of sperm donors on a connection website

STUDY QUESTION What are the demographic characteristics, motivations, preferences and experiences of heterosexual, gay and bisexual sperm donors on a connection website (i.e. a website that facilitates direct contact between donors and recipients of gametes)?

Effects of fertility education on knowledge, desires and anxiety among the reproductive-aged population: findings from a randomized controlled trial

STUDY QUESTION What are the effects of fertility education on knowledge, childbearing desires and anxiety?

Advanced maternal age causes adverse programming of mouse blastocysts leading to altered growth and impaired cardiometabolic health in post-natal life

STUDY QUESTION Does advanced maternal age (AMA) in mice affect cardiometabolic health during post-natal life in offspring derived from an assisted reproduction technology (ART) procedure?

Copy number variation analysis detects novel candidate genes involved in follicular growth and oocyte maturation in a cohort of premature ovarian failure cases

STUDY QUESTION Can spontaneous premature ovarian failure (POF) patients derived from population-based biobanks reveal the association between copy number variations (CNVs) and POF?

Assisted reproductive technology in Europe, 2012: results generated from European registers by ESHRE†

STUDY QUESTION The 16th European IVF-monitoring (EIM) report presents the data of the treatments involving assisted reproductive technology (ART) and intrauterine insemination (IUI) initiated in Europe during 2012: are there any changes compared with previous years?

Risk of recurrent molar pregnancies following complete and partial hydatidiform moles