Background: Lung diseases are assuming greater relevance and importance today. Chronic bronchitis is a self-nosology, which may precede the development of COPD, the importance of which can hardly be overestimated. The main problem in this disease is caused by late diagnosis and treatment due to the delay by patients in seeking medical help. The aim of the work was to study the...
The implantation of the Bone Marrow Mesenchymal Stem Cells (BMSCs) into the heart has been reported to be effective for the treatment of myocardial infarction; however, the methods most suitable for supporting stem cell growth in a myocardial patch, still remain unknown. We used a new polymer material composed of poly(3-hydroxybutyrate-co-3-hydroxybutyrate) [P(3HB-co-3HB)] co...
The presence of the causal effects between the pollution of the environment of the urbanized territories and the population morbidity with enteric infections was confirmed from the evidence collected by calculating the positive meanings of the Odds Ratio (OR) and Relative Risk (RR) with trusted confidential borders, Identified Density Ratio (IDR) and associated risks, as well as...
Background: The primary objective was to examine and compare the breast cancer screening adherence rates between black (African American and Afro-Caribbean) and Hispanic (foreign born Hispanic and US-born Hispanic) subpopulations. Methods: Study data was collected in community settings in New York City between the years of 2011-2012. Participants (N=592) were black and Hispanic...
A study of the carbohydrate and lipid metabolism, as well as the leptin level was conducted in 69 patients with chronic pancreatitis (CP) associated with the metabolic syndrome (MS). The results revealed significant changes in the serum parameters studied in patients with CP and MS. The authors concluded that in such patients, the irregularities in the glucose-insulin homeostasis...
The study included rheumatoid arthritis patients from three regions of Uzbekistan, viz., Tashkent city - zone I (n=144), Khorezm region – zone II (n=112) and the Namangan region – zone III (n=104). Comparative clinical and laboratory analyses showed the clear evidence of aggressive joint syndrome dominance in zone II (71.4%), which was higher than those of the patients in zone...
Based on the current study, the clinical characteristics of unipolar depression in the clinical picture of schizophrenia with the paroxysmal type of disease course are presented. Given the concomitant depression with phobic symptoms, the following clinical variants are marked: depression with generalized social phobia and/or anthropophobia and depression with generalized...
Background: Radiotherapy is the keystone in brain tumor treatment, including posterior fossa tumors, and can achieve better patient health-related quality of life. Radiation exposure can be associated with the risk of skin radiation injuries. Accurate tumor and critical structure delineations and precise dose planning may improve the outcomes and decrease radiation complications...
The present study focused on the impact of lignane syringaresinol beta-D-monoglucoside (substance 1) on the healing process of the linear and planar wounds in white male Wistar rats, with a body mass ranging between 180 and 200g. This substance was found to contribute towards quicker healing of the wound damage, when compared with solcoseryl. Thus, the solidity of the cicatrix...
Although the immune component of the pathogenesis of schizophrenia is well documented and recognized, the characteristics of the relationship between nonspecific and specific immune resistance and their correlation with the form and course of the disease continue to remain practically unexplored. The aim of this study was to investigate the systemic relationships present between...
Proliferation and differentiation of cells occur in the morphofunctional zones, in the electric field excited by 12 pairs of mother and daughter cells, produced by cambial cell division. Thus, in the daughter cells, the Src SH2 domain is essential for both cytoskeleton formation and tyrosinase activation. If the conditions for strengthening the tyrosinase activity are created in...
The purpose of this study was to evaluate the heart rate variability (HRV) level and the features of early post-infarction left ventricular remodeling (PIR) in patients with recurrent myocardial infarction (MI), which developed within six months post the initial Q-wave MI (Q-MI). Material and Methods: The study surveyed 105 male patients between 29 and 69 years of age (mean age...
This presentation reviews data from studies on the encephalon in 27 men ranging in age from 21 to 51 years, showing signs of chronic alcohol intoxication and who died from causes other than skull injury and 14 control subjects. The specimens were fixed in formalin or Karnua liquid, filled with paraffin and then examined, utilizing a variety of histological, histochemical and...
The aim of our study was to examine the cognitive functions in patients with chronic cerebral ischemia (stages I- II of discirculatory encephalopathy) of various origins. Systematization of the patients was performed according to EV Schmidt’s classification of the vascular lesions of the brain. All the subjects were categorized into two groups. Group 1 consisted of 115 patients...
Duchenne Muscular Dystrophy (DMD) is a severe, progressive disease that affects about 1 out of every 5,000 male infants; this is the most destructive of all muscular dystrophies, which worsens rapidly. In this study, we performed a clinical analysis of 37 children with DMD. They ranged in age from 3 to 15 years, mean age being 7.8±0.48 years. The mean age at onset was 4.3±0.36...
Juvenile Idiopathic Arthritis (JIA) is the commonest and most debilitating rheumatic disease occurring among children. Objective: To identify the frequency and nature of the menstrual disorders observed in girls affected with JIA. Material and Methods: The study included 147 patients of the Rheumatology department of St. Petersburg State Pediatric Medical University’s clinic, 58...
The aim of the study was to analyze the results of the surgical treatment in pediatric patients who had undergone the Ross procedure.Material and Methods: The study involved 114 patients between 12 days to 18 years in age. The early and late (up to 5 years) results of the treatment were studied. The examination included echocardiography, catheterization of the cardiac chambers...
The aim of this study was to evaluate the metabolic features of nitric oxide (NO) in patients with chronic heart failure (CHF) of ischemic origin. The study included 303 patients with ischemic CHF who received the standard treatment for CHF. Evaluation of the functional status of the NO system included the detection of arginine concentrations in the peripheral blood, stable...
Systemic osteoporosis can damage skeletal bones to different degrees or remain persistent in intensity. The aim of this study was to determine the intensity and correlation of the osteoporotic changes in the bone density of the skeleton and body mass index (BMI) with a reduction in edentulous mandibles. Material and Methods: In this study, 89 edentulous patients with decreased...
Chronic cerebral ischemia (CCI), as a manifestation of age-related pathology shows strong parameters of the morbidity rate among the elderly. Cognitive impairments are one of main expressions of this pathology. The aim of this study was to evaluate the neurophysiological parameters of the cognitive impairments in patients with various stages of discirculatory encephalopathy (DE...
Inborn errors of metabolism (IEM) are a heterogeneous group of monogenic diseases that affect the metabolic pathways. The detection of IEM relies on a high index of clinical suspicion and co-ordinated access to specialized laboratory services. Biochemical analysis forms the basis of the final confirmed diagnosis in several of these disorders. The investigations fall into four...
Background: Spheroid cell structures (SCS) described in cell culture are used to study cell-cell and cell-matrix interactions. However, the role of the SCS in the repair process in vivo remains unexplored. The aim of the study was to examine the cellular composition of the spherical structures and their functional significance in the repair of the squamous epithelium in human...
The frequency characteristics of the gene polymorphisms (FVL G1691A, FII G20210A, MTHFR C677T, MTHFR A1298C, MTRR A66G) associated with thrombophilia, hyperhomocysteinemia risk and different perinatal or pregnancy complications were studied. This examination was conducted among 130 planned-pregnancy healthy young women aged between 19 and 29 years. A gene mutation analysis was...
The aim of the study was to evaluate the effect of a low protein diet (LPD) balanced with essential amino acids (EAA) / keto acid analogs (KAA) and protein “SUPRO-XT 219D” in the composition of the high-energy nutrient blend (HENB) for slow down of renal failure in patients in the pre-dialysis stage of chronic kidney disease (CKD) induced by systemic autoimmune diseases (SAD...
Objective: This study evaluated the mesiodistal crown sizes of the remaining dentition in patients affected with hypodontia, compared with the control group possessing complete dentition. Methods: Panoramic radiographs of the patients treated in the Department of Orthodontics, Dental School - branch of Medical Faculty – University of Pristina, were reviewed to select a sample of...