The aim of this study was to get an experimental estimation of the anti-inflammatory and immunomodulating properties of the complex plant remedy. The subject of this study was complex plant remedy that has been developed based on the recipes of Tibetan medicine. Experiments were conducted on Wistar rats and male mice of the CBA genetic strain. The anti-inflammatory properties of...
The purpose of this study was to study the effects of L-arginine on the clinical course and some immunological parameters in patients with asthma. Material and Methods: In this study, we examined 56 patients with moderate and severe persistent asthma. The duration of the disease ranged between 15+2. 3 years. The patients were divided into two groups. The patients of the study...
In this study, the earlier used method to measure the dynamics of shape changes in red blood cells (RBCs), based on an analysis of light fluctuations in the suspension, was modified to allow for the simultaneous recording of cell volume changes after appropriate recalculation of the raw absorbance and shape index data. With this improved methodology, we investigated the...
The study has been performed to compare the immediate and long-term outcomes of Vitreoretinal Surgery (VS) on patients with Proliferative Diabetic Retinopathy (PDR) in relation to Prior Retinal Laser Coagulation (PLC). The study included 56 patients (71 eyes) with diabetes mellitus (type 2 - 52/93%, men – 39/75%) complicated with proliferative diabetic retinopathy (PDR...
Every organism is composed of multi-cellular systems. Each of these cells, from the time of birth until death, often plays a polyfunctional role. Obviously, this cycle must include periods of intense work and leisure. In other words, the organ cell masses are able to perform the asynchronous mechanism of cell cycle. The implementation of such a mechanism is regulated by the cell...
In this work, the surface-active properties of 1- boraadamantane have been studied on the model of monomolecular phospholipid monolayers. Compression isotherms for the phospholipid monolayer are received, before the addition of 1-bromoadamantane in a concentration of 10-7-10-6 M. From the analysis of the compression isotherms generated, it is possible to conclude that at a...
The article discusses the main issues of the endothelial function and dysfunction.
Significant changes in the levels of the potential prooxidant Cu (increase) and the antioxidant Zn (decrease) in plasma were revealed in children having bronchopulmonary dysplasia (BPD) complicated by pulmonary arterial hypertension (PAH) and chronic cor pulmonale (CCP) when compared with the control. The Zn / Cu ratio in the blood plasma of patients with BPD, especially in CCP...
The problem of early diagnostics of bacterial complications is particularly true for children with extensive burn trauma (BT). Procalcitonin concentration levels considerably facilitate the diagnosis of sepsis. In all, 50 children with severe burns were included in our research. We conducted histological tests of the burn wound tissues from 13 patients. On comparison of the...
In this paper, the proposed cholecystectomy method for very large Hartmann’s pouch spliced with biliary pathways is described in detail. The results of the cholecystectomy procedure for very large Hartmann’s pouch spliced with biliary pathways during the period 2001-2012 are presented. The proposed method contributes to a reduction in complications such as bleeding and bile...
This paper presents the results of research and treatments in 41 children (from two months to 15 years of age) with urethral valves. In all, 16 patients were treated using the endoscopic method, 7 patients by employing the polyethylene urethrotome and 18 patients treated by the proposed method, using a metallic urethrotome. Diagnosis of the urethral valves was done using...
The aim of this study was to assess the fatty acid balance in the blood plasma, in the fragments of the intact vessels and the vessels showing signs of atherosclerosis.Material and Methods: The article presents the results of the examination of the blood plasma samples of patients with coronary heart disease and coronary atherosclerosis. The control group consisted of 16 healthy...
The aim of this study was to improve the principles of the pathogenetic therapy of acute pancreatitis and assess the effectiveness of local hypothermia of the pancreas, as well as peritoneal lavage-dialysis in the treatment of acute destructive pancreatitis. A total of 5889 patients with acute pancreatitis (AP) were examined. The leading role played by the lesions of the...
Immunocytochemistry was performed on the cells taken from the ecto/endocervix and endometrium. The monoclonal antibodies produced against CD20, CD56 and TLR have been used in the immunocytochemistry. The frequency of the immunocytochemically positive cells was estimated before and after a course of sodium nucleospermate treatment, in women suffering from infertility. The real...
In this study, the transport of the long chain polyunsaturated fatty acids (LCPUFAs) from the lacunar blood through the syncytiotrophoblast of the placental villi to the fetal cord blood via a saturable protein-mediated mechanism by the heart-type fatty acid-binding proteins (H-FABPs) has been examined. Exacerbation of the herpes simplex viruses (HSV-1) in the third trimester of...
The genetic structure of Helicobacter in children with gastroduodenal pathology and the regional distribution of the pathogenic genes of Helicobacter pylori (CagA and VacA) were established. Almost all the Helicobacter pylori (HP) strains showed the presence of gene toxicity (tox+) of 71.7%. The spectrum of toxigenic HP genes shows the following distribution: CagA+ defined in 70...
The study of the physical development of pupils over the last 50 years has established some features regarding the formation of morphological and functional parameters of schoolchildren. The studies were conducted using longitudinal and cross-sectional methods, which contribute to a more detailed analysis of the results. The lifestyle of students in Moscow and the factors...
The lymphatic system consists of two types segments – general (systemic or periarterial) and special (own, intervalvular). The segments organize all the system’s reactions in response to its environmental influences. This paper presents the results of the research the common structure of all the sections of the lymphatic bed.
The aim of the study was to identify the predictors of treatment-resistant depression (TRD) with positive affectivity. The article presents the results of the examination of 96 patients with TRD. The studied patients were divided into two groups: in the first group consisted of patients with TRD having positive affectivity (n=59), in the second group consisted of patients with...
Background: For nearly a decade, a disease likely to have been misdiagnosed was observed in pregnant women in Tashkent, Uzbekistan. It caused the rapid decline and death of patients, with about 45% mortality rate. The disease was suspected to be caused by a virus of the HVP (Hantavirus) family, and clinical studies were conducted to ascertain. Methods: As no system for...
Objective: To study the distribution of I/D polymorphic marker of the ACE gene in Uzbek patients with unstable angina, depending on the presence of family history of CHD compared with healthy individuals. Materials and methods: There were examined 125 Uzbek patients with unstable angina (class IIB by E. Braunwald et al., 1989). In patients with unstable angina 63 patients (the...
The epidermis of 60 mice ears is investigated in this study. The proliferative activity of the epidermal basal cells over 24h was observed to occur in two active phases (АP) and 2 passive phases (PP). The АP phase in turn consists of two subphases. Subphase 1, the longer of the two, is a proliferation of the descendants of the cambial cells; Subphase 2, is very short, involving a...
All forms of psoriasis show an increase in the presence of certain cytokines, including, IL-2, IL-6, IL-8 and TNF-alpha, with the last one revealing direct participation in the pathogenesis of dermatosis as modern biological therapeutic agents act directly on the activation of this cytokine. A study of the cytokine profile shows Th1-type immune response in the psoriasis patients...
Creating mechanochemical bio-complexes based on the natural matrix of the lichen β-oligosaccharide leads to a prolongation of the pharmacon and increases its biological (including therapeutic) effect by a few times, while reducing the dose and toxicity.
Diseases of the ENT organs are among the commonly prevalent and dangerous pathologies of childhood, occurring as a complication of respiratory, bacterial diseases and HIV infection. One of the serious complications of HIV infection in children is the lesion of ENT organs. In HIV infected children, in addition to suppurative diseases occur middle ear diseases with nonsuppurative...